Endocrine Abstracts

Background: High levels of mannose-binding lectin (MBL), an activator of complement, have been associated with increased mortality and risk of albuminuria in patients with type 2 diabetes. It is not known if MBL is synthesized in human adipose tissue and the effects of weight loss and changes in insulin sensitivity on MBL levels have been poorly elucidated.Methods: Of 36 nondiabetic obese subjects received a very low-calorie diet (VLCD) of 800 kcal/day f...

Introduction: Type 2 diabetes is associated with accelerated atherosclerosis, which causes macro-vascular complications such as cerebral infarctions, myocardial infarctions, and peripheral vascular disease. We aimed to investigate whether there are differences in the morphology of atherosclerosis in the carotid arteries assessed by MRI in newly diagnosed type 2 diabetic patients compared to non-diabetic control subjects.Methods: Hundred type 2 diabetic p...